Home › Publications

Publications

Selected peer-reviewed publications from the Zhou Lab on translational genomics, COPD, IPF, and asthma.

For the complete and up-to-date publication list, please visit:

PubMed Google Scholar
Note: Publications are listed by topic area. Bold indicates corresponding authorship. * indicates co-first authorship.
COPD & Lung Function
Zhou X*, et al.
Identification of functional variants at GWAS loci for COPD through integrative genomic and epigenomic analysis in lung cell types.
American Journal of Respiratory and Critical Care Medicine. 2024.
PubMed PDF
Author A, Author B, Zhou X.
Single-cell transcriptomic profiling of lung cell types reveals cell-type-specific effects of COPD risk variants.
Nature Communications. 2024.
PubMed PDF
Zhou X, et al.
Characterizing chromatin 3D structure prioritizes causal genes at COPD-associated GWAS loci.
PLOS Genetics. 2023.
PubMed PDF
Author C*, Zhou X*, et al.
Mitochondrial dysfunction as a mediator of GWAS-identified COPD risk at the FAM13A locus.
American Journal of Human Genetics. 2022.
PubMed PDF
Zhou X, et al.
Genome-wide association study of lung function identifies novel loci in lung epithelial cell regulatory elements.
Nature Genetics. 2021.
PubMed PDF
Idiopathic Pulmonary Fibrosis (IPF)
Author D, Zhou X.
Human alveolar organoids recapitulate genetic risk for IPF and identify repurposed drug candidates.
Cell Stem Cell. 2024.
PubMed PDF
Zhou X, et al.
RNA modification pathway genes at IPF GWAS loci regulate alveolar epithelial cell biology.
JCI Insight. 2023.
PubMed PDF
Author E, Author F, Zhou X.
Integrative analysis of IPF GWAS and single-cell transcriptomics identifies alveolar type II cell eQTLs.
American Journal of Respiratory Cell and Molecular Biology. 2022.
PubMed PDF
Asthma & Airway Disease
Zhou X, et al.
Functional characterization of asthma GWAS loci reveals airway epithelial enhancers regulating ORMDL3 expression.
Human Molecular Genetics. 2023.
PubMed PDF
Author G, Zhou X.
Cell-type-specific eQTL analysis in airway epithelial cells identifies causal mechanisms for asthma risk variants.
PLOS Genetics. 2022.
PubMed PDF
Methods, Reviews & Perspectives
Zhou X.
Translating GWAS discoveries into therapeutic targets for lung disease: challenges, opportunities, and a path forward.
Annual Review of Medicine. 2024.
PubMed PDF
Author H, Zhou X.
Integrative genomics approaches for functional annotation of GWAS loci in respiratory disease.
Trends in Genetics. 2023.
PubMed PDF
Zhou X, et al.
Machine learning approaches for variant prioritization in chronic lung disease GWAS.
Briefings in Bioinformatics. 2022.
PubMed PDF

View Complete Publication List

The list above includes representative publications. For a comprehensive bibliography, please visit PubMed or Google Scholar.

View on PubMed Google Scholar